49ers' 2022 schedule among the toughest in strength-of-schedule rankings

49ers’ 2022 schedule among the toughest in strength-of-schedule rankings

Cary Edmondson-USA TODAY Sports The NFL will announce the entire 2022 slate of matchups on Thursday night. That’s when we’ll learn the dates and times for all 272 regular-season games. However, we’ve known the opponents for a while now. If the San Francisco 49ers are to return to the playoffs for the third time in …

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